Publications

1. Donepezil hydrochloride (Aspen) for the indication symptomatic treatment of mild to moderately severe Alzheimer’s dementia

   The WAR has drawn up a pharmacotherapeutic report for the medicine donepezil (hydrochloride) Aspen film-coated tablets. Its ...

   Report | 24-06-2013

2. Ruxolitinib (Jakavi) for the indication symptomatic treatment of myelofibrosis

   Ruxolitinib has an added value in comparison with placebo or BAT in the treatment of the disease-related splenomegaly or symptoms ...

   Report | 22-04-2013

3. Ulipristal (Esmya) for preoperative treatment of moderate to severe symptoms of uterine fibroids in adult women of reproductive age

   The applicant claims that treatment with ulipristal is a cost-effective intervention for the preoperative treatment of moderate ...

   Report | 25-03-2013

4. Ivabradine (Procoralan) for the indication chronic heart failure

   Ivabradine has an added therapeutic value in comparison with placebo in patients with chronic heart failure HYHA class II-IV in ...

   Report | 25-03-2013

5. Apixaban (Eliquis) for prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation

   For the prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation with one of more risk ...

   Report | 25-02-2013

6. Fidaxomycin (Dificlir) for the indication Clostridium difficile-related disease

   In the treatment of patients with CDAD who are severely ill or who have been admitted to hospital, the therapeutic value of ...

   Report | 25-02-2013

7. Endoluminal fundoplication with EsophyX incases of gastro-oesophageal reflux

   There is insufficient evidence of a good methodological quality to be able to conclude that endoluminal fundoplication with ...

   Report | 18-02-2013

8. Treating severe asymptomatic A. carotid stenosis in combination with an indicated bypass operation or heart valve surgery

   CVZ’s reply to this question is negative: the above-mentioned treatment does not fulfil the established medical science and ...

   Report | 21-12-2012

9. Endobronchial lung volume reduction by means of one-way valves in cases of emphysema

   In this outcome CVZ assessed whether using one-way valves to reduce endobronchial lung volume (BLVR) in cases of emphysema can be ...

   Report | 21-12-2012

10. Fampridine (Fampyra) for the indication ‘improvement in MS patients’ walking ability

    The therapeutic value of fampridine is the same as that of pharmacy-compounded fampridine (=4-AP) in improving the walking ...

    Report | 17-12-2012