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  1. Ivabradine (Procoralan) for the indication chronic heart failure

    Ivabradine has an added therapeutic value in comparison with placebo in patients with chronic heart failure HYHA class II-IV in ...

    Report | 25-03-2013

  2. Apixaban (Eliquis) for prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation

    For the prevention of stroke and systemic embolism in adult patients with non-valvular atrial fibrillation with one of more risk ...

    Report | 25-02-2013

  3. Fidaxomycin (Dificlir) for the indication Clostridium difficile-related disease

    In the treatment of patients with CDAD who are severely ill or who have been admitted to hospital, the therapeutic value of ...

    Report | 25-02-2013

  4. Endoluminal fundoplication with EsophyX incases of gastro-oesophageal reflux

    There is insufficient evidence of a good methodological quality to be able to conclude that endoluminal fundoplication with ...

    Report | 18-02-2013

  5. Treating severe asymptomatic A. carotid stenosis in combination with an indicated bypass operation or heart valve surgery

    CVZ’s reply to this question is negative: the above-mentioned treatment does not fulfil the established medical science and ...

    Report | 21-12-2012

  6. Endobronchial lung volume reduction by means of one-way valves in cases of emphysema

    In this outcome CVZ assessed whether using one-way valves to reduce endobronchial lung volume (BLVR) in cases of emphysema can be ...

    Report | 21-12-2012

  7. Fampridine (Fampyra) for the indication ‘improvement in MS patients’ walking ability

    The therapeutic value of fampridine is the same as that of pharmacy-compounded fampridine (=4-AP) in improving the walking ...

    Report | 17-12-2012

  8. Alitretinoin (Toctino) for the indication preoperative treatment of severe chronic hand eczema

    The applicant claims that treatment with alitretinoin is a cost-effective intervention for the treatment of severe chronic hand ...

    Report | 17-12-2012

  9. Crisantaspase (Erwinase) for the indications acute lymphatic leukaemia & lymphoblastic non-Hodgkin lymphoma

    Asparaginase is an important part of treatment of ALL and lymphoblastic non-Hodgkin lymphoma. The use of asparaginase has been ...

    Report | 17-12-2012

  10. Aclidinium (Eklira Genuair ) for the indication ‘COPD’

    For the treatment of COPD, the therapeutic value of aclidinium is equal to that of tiotropium. This report is a summary of ...

    Report | 26-11-2012

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