Publications
484 publications
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Pravastatin/fenofibrate (Pravafenix) for the indication ‘dyslipidaemia with high-concentration triglycerides’
The use of pravastatin/fenofibrate to treat adult patients with an increased risk of coronorary heart disease and who suffer from ...
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Pasireotide (Signifor) for the indication ‘Cushing’s Disease’
The results of these studies indicate only that these drugs are effective and safe in patients from whom surgery is not an option ...
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Vandetanib (Caprelsa) for the indication ‘metastatic medullary thyroid cancer’
Vandetanib has a therapeutic added value in comparison with placebo for the treatment of aggressive and symptomatic medullary ...
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Tegafur/gimeracil/oteracil (Teysuno) for the indication ‘advanced gastric cancer’.
The standard treatment triplet has been proven to have a significant survival advantage in comparison with a doublet without ...
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Eribulin (Halaven) for the indication ‘patients with locally advanced or metastatic breast cancer’.
The therapeutic added value of eribulin is equal to that of TPC. Based on this comparison, however, it is impossible to say ...
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Albumin-bound paclitaxal (Abraxane) for the indication ‘metastatic breast cancer’
The conclusion is that the therapeutic value of NAB-paclitaxel is comparable to that of SB-paclitaxel in the second-line or ...
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Endovascular treatment of complex aneurysms of the aorta
This assessment shows that there is insufficient evidence of high methodological quality to be able to conclude that the ...
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Dabigatran etexilate (Pradaxa) for the prevention of stroke and systemic embolism in adult patients with nonvalvular atrial fibrillation
For the prevention of stroke and systemic embolism in adult patients with nonvalvular atrial fibrillation with one or more risk ...
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Assessment of the services provided by the Forensic Child Abuse Center
The Forensic Medical Child Abuse Center asked CVZ to assess whether the various activities of the FPKM can be regarded as medical ...
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Collagenase clostridium histolyticum (Xiapex) for the indication ‘treatment of Dupuytren's contracture
On the basis of a comparison between collagenase studies and fasciectomy studies, no statement can be issued about the efficacy ...